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$25
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- Proposals: 2
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Description
Experience Level: Entry
Project title: Educational health blog articles.
Category: Health and Fitness
Keyword: Liver Disease and Oxidative Stress
Word count:1000
Writing style: Professional tone
Article purpose: Educational articles for use in company blog. Articles should be supportive to company products. We will be editing the end of each article to include a plug regarding company products.
Special instructions: If you can discuss the role oxidative stress plays in the pathogenesis of liver damage/disease and then tie in what limited data there is on the benefits of glutathione to liver health
Here are some studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661801/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081679/
This one you have to purchase but the summary is still useful
https://www.ncbi.nlm.nih.gov/pubmed/27603810
Liver diseases markedly contribute to the global burden of mortality and morbidity. The pathogenesis of alcohol- and non-alcohol-induced liver diseases is complex, and many factors have been described to contribute to the progressive loss of liver functions, including the over-generation of reactive oxygen species. Glutathione (GSH) is the most important low-molecular-weight antioxidant synthesized in cells, as it is a reducing molecule which can react to oxygen species by neutralizing the unpaired electrons that make them highly reactive and dangerous. ROS over-production impairs the intracellular GSH homeostasis, leading to GSH deficiency, a pathophysiological hallmark in alcoholic and non-alcoholic liver diseases.Judging on the basis of the evidence obtained from experimental research and previous clinical studies, GSH administration seems to be a promising strategy to recover oxidative stress-induced liver damages in alcoholic and non-alcoholic liver diseases.
Some references
http://glutathionepathway.com/glutathione-liver-health/
http://www.wellwisdom.com/oxidative-stress-in-liver-disease-glutathiones-role/
Category: Health and Fitness
Keyword: Liver Disease and Oxidative Stress
Word count:1000
Writing style: Professional tone
Article purpose: Educational articles for use in company blog. Articles should be supportive to company products. We will be editing the end of each article to include a plug regarding company products.
Special instructions: If you can discuss the role oxidative stress plays in the pathogenesis of liver damage/disease and then tie in what limited data there is on the benefits of glutathione to liver health
Here are some studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661801/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081679/
This one you have to purchase but the summary is still useful
https://www.ncbi.nlm.nih.gov/pubmed/27603810
Liver diseases markedly contribute to the global burden of mortality and morbidity. The pathogenesis of alcohol- and non-alcohol-induced liver diseases is complex, and many factors have been described to contribute to the progressive loss of liver functions, including the over-generation of reactive oxygen species. Glutathione (GSH) is the most important low-molecular-weight antioxidant synthesized in cells, as it is a reducing molecule which can react to oxygen species by neutralizing the unpaired electrons that make them highly reactive and dangerous. ROS over-production impairs the intracellular GSH homeostasis, leading to GSH deficiency, a pathophysiological hallmark in alcoholic and non-alcoholic liver diseases.Judging on the basis of the evidence obtained from experimental research and previous clinical studies, GSH administration seems to be a promising strategy to recover oxidative stress-induced liver damages in alcoholic and non-alcoholic liver diseases.
Some references
http://glutathionepathway.com/glutathione-liver-health/
http://www.wellwisdom.com/oxidative-stress-in-liver-disease-glutathiones-role/
Carolyne K.
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Projects awarded
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Last project
29 Jun 2017
United States
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